Organoid Technology: Disease Modelling, Drug Discovery and Personalized Medicine

Organoids are miniature in vitro 3D models that mimic the near-physiological structure and function of the respective tissues and organs. Organoid bioengineering is a transdisciplinary approach that uses stem cells capacity to self-renew, differentiate into several lineages, and self-organize into organoids. Using organoid bioengineering, scientists have employed induced pluripotent stem cells (iPSCs), embryonic stem cells (ESCs), and tissue-resident adult stem cells (ASCs) to generate these tiny tissue replicas.